N-[(1E)-(3-Bromophenyl)methylene]-N- (2-piperidin-1-ylethyl)amine

نویسندگان

  • Ismail Warad
  • Yasmin Al-Demeri
  • Mohammmed Al-Nuri
  • Mohammed Suleiman
  • Anas Al-Ali
  • Sameer Amereih
چکیده

N-[(1E)-(3-Bromophenyl)methylene]-N-(2-piperidin-1-ylethyl)amine Schiff base was prepared in good yield and characterized by the reflux of equivalent amounts of 2-(piperidin-1-yl)ethanamine with 3-bromobenzaldehyde. The structure of the desired Schiff base was analyzed based on: elemental analysis, EI-MS, TG/DTG, UV-visible, FT-IR, 1H and 13C-NMR spectral analysis. The condensation reaction was monitored by FT-IR.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Antiprotozoal activity of (E)-cinnamic N-acylhydrazone derivatives.

A series of 14 (E)-cinnamic N-acylhydrazone derivatives, designed through molecular hybridization between the (E)-1-(benzo[d][1,3]dioxol-5-yl)-3-(4-bromophenyl)prop-2-en-1-one and (E)-3-hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)-7-methoxy-2-naphthohydrazide, were tested for in vitro antiparasitic activity upon axenic amastigote forms of Leishmania donovani and bloodstream forms of Trypamo...

متن کامل

N-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor.

On the basis of N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine (II, ASS234) and QSAR predictions, in this work we have designed, synthesized, and evaluated a number of new indole derivatives from which we have identified N-methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine (2, MBA236) as ...

متن کامل

Crystal structure of di-μ-iodido-bis{[bis(piperidin-1-yl)methane-κ2 N,N′]copper(I)}

The title compound, [Cu2I2(C11H22N2)2], crystallizes as a symmetric dimer with one quarter of the mol-ecule in the asymmetric unit. The copper(I) atom, the iodine atom and the central methyl-ene C atom of the di(piperidin-1-yl)methane ligand lie on a mirror plane and the complete molecule exhibits point group symmetry 2/m. To the best of our knowledge it is the first di-amine copper(I) complex ...

متن کامل

[2-(Piperidin-1-yl)ethyl­amine]dithio­cyanato­zinc(II)

In the mononuclear title compound, [Zn(NCS)(2)(C(7)H(16)N(2))], the Zn(II) atom is four-coordinated by two N atoms of the chelating 2-(piperidin-1-yl)ethyl-amine ligand and two N atoms from two thio-cyanate ligands in a distorted tetra-hedral geometry. In the crystal structure, mol-ecules are linked through inter-molecular N-H⋯S hydrogen bonds, forming chains along the b axis.

متن کامل

Crystal structures of four δ-keto esters and a Cambridge Structural Database analysis of cyano-halogen interactions.

The revived interest in halogen bonding as a tool in pharmaceutical cocrystals and drug design has indicated that cyano-halogen interactions could play an important role. The crystal structures of four closely related δ-keto esters, which differ only in the substitution at a single C atom (by H, OMe, Cl and Br), are compared, namely ethyl 2-cyano-5-oxo-5-phenyl-3-(piperidin-1-yl)pent-2-enoate, ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016